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Fig. 1 | Journal of Inflammation

Fig. 1

From: Regulatory effects of statins on CCL2/CCR2 axis in cardiovascular diseases: new insight into pleiotropic effects of statins

Fig. 1

The CCL2/CCR2 axis plays a crucial role in the pathogenesis of atherosclerosis. Statins significantly interfere with the development and progression of atherosclerotic lesions by modulating the CCL2/CCR2 pathway as depicted(inspired by [209]). This figure shows how statins interfere with the migration of monocytes into the subendothelial layer, the production of collagen by smooth muscle cells (SMCs), lipid accumulation, and instability of developed plaques

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Journal of Inflammation

ISSN: 1476-9255

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