Affiliated with the British Inflammation Research Association (BIRAs).
Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways
IκBα is an inhibitor of the nuclear transcription factor NF-κB. Binding of IκBα to NF-κB inactivates the transcriptional activity of NF-κB. Expression of IκBα itself is regulated by NF-κB, which provides auto-...