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Articles

Page 15 of 17

  1. Prostaglandin E2 (PGE2), experimentally administered to asthma patients or assayed in murine models, improves allergen-driven airway inflammation. The mechanisms are unknown, but fluctuations of the endogenous cy...

    Authors: Aida Herrerias, Rosa Torres, Mariona Serra, Alberto Marco, Laura Pujols, César Picado and Fernando de Mora
    Citation: Journal of Inflammation 2009 6:30
    Content type: Research Published on:

  2. The role of protein kinase C (PKC) in regulating the activity of phospholipase C (PLC) in neutrophils activated with the chemoattractant, platelet-activating factor (PAF, 20 and 200 nM), was probed in the curr...

    Authors: Gregory R Tintinger, Annette J Theron, Helen C Steel, Riana Cockeran, Lynette Pretorius and Ronald Anderson
    Citation: Journal of Inflammation 2009 6:29
    Content type: Research Published on:

  4. Homocysteine (Hcy) and inflammatory cytokines have been linked to adverse outcomes in persons with cardiovascular and kidney diseases and recent reports suggest that cytokine-mediated inflammatory infiltrates ...

    Authors: Suresh Shastry and Leighton R James
    Citation: Journal of Inflammation 2009 6:27
    Content type: Research Published on:

  5. Rho iso-alpha acids (RIAA) from hops have been shown to have anti-inflammatory properties. To understand the mechanisms, we evaluated the effect of RIAA in cell signaling pathways and inflammatory markers using v...

    Authors: Veera Reddy Konda, Anuradha Desai, Gary Darland, Jeffrey S Bland and Matthew L Tripp
    Citation: Journal of Inflammation 2009 6:26
    Content type: Research Published on:

  6. Various cytokines and other compounds are produced in human adipose tissue and might have functions in the adipose tissue. They might be involved in complications associated with obesity and diabetes. Recently...

    Authors: Chikaaki Kobashi, Sachie Asamizu, Manabu Ishiki, Minoru Iwata, Isao Usui, Katusuya Yamazaki, Kazuyuki Tobe, Masashi Kobayashi and Masaharu Urakaze
    Citation: Journal of Inflammation 2009 6:25
    Content type: Short Report Published on:

  7. The pleiotropic protein MIF, (macrophage migration inhibitory factor), has been demonstrated to modulate several key proteins governing cell cycle control and is considered to contribute to cell growth and dif...

    Authors: Elliott Taranto, Jin R Xue, Eric F Morand and Michelle Leech
    Citation: Journal of Inflammation 2009 6:24
    Content type: Research Published on:

  8. The pluripotent cytokine transforming growth factor-β1 (TGF-β1) is the central regulator of inducible Nitric Oxide Synthase (iNOS) that is responsible for nitric oxide (NO) production in inflammatory settings....

    Authors: Pradeep Tyagi, Vikas Tyagi, Naoki Yoshimura, Erich Witteemer, Derek Barclay, Patricia A Loughran, Ruben Zamora and Yoram Vodovotz
    Citation: Journal of Inflammation 2009 6:23
    Content type: Research Published on:

  9. Herpesviruses have evolved chemokines and chemokine receptors, which modulate the recruitment of human leukocytes during the inflammatory response to infection. Early post-infection, human herpesvirus 6A (HHV-...

    Authors: Julie Catusse, David J Clark and Ursula A Gompels
    Citation: Journal of Inflammation 2009 6:22
    Content type: Research Published on:

  10. There are several reports suggesting that hyperosmolarity induces inflammation. We recently showed that Dextran Sodium Sulfate causes inflammatory bowel disease due to hyperosmolarity. The aim of this study wa...

    Authors: Laurent Schwartz, Adeline Guais, Mohammad Pooya and Mohammad Abolhassani
    Citation: Journal of Inflammation 2009 6:21
    Content type: Research Published on:

  11. The peptidyl-proline isomerase, Protein Never in Mitosis Gene A Interacting-1 (PIN1), regulates turnover of inducible nitric oxide synthase (iNOS) in murine aortic endothelial cells (MAEC) stimulated with E. coli

    Authors: Tongzheng Liu, Ryan A Schneider, Vaibhav Shah, Yongcheng Huang, Rostislav I Likhotvorik, Lakhu Keshvara and Dale G Hoyt
    Citation: Journal of Inflammation 2009 6:20
    Content type: Research Published on:

  12. Cadmium is one of the inflammation-related xenobiotics and has been regarded as a potent carcinogen. The relationship between inflammation and cell proliferation due to chronic infection has been studied, but ...

    Authors: Subhadip Kundu, Suman Sengupta, Soumya Chatterjee, Soham Mitra and Arindam Bhattacharyya
    Citation: Journal of Inflammation 2009 6:19
    Content type: Research Published on:

  13. Neuromyelitis optica is a central nervous system demyelinating and inflammatory syndrome. The objective of this study is to identify cytokines related to the cellular immune response as well as blood brain bar...

    Authors: Giselle Pentón-Rol, Majel Cervantes-Llanos, Gregorio Martínez-Sánchez, José A Cabrera-Gómez, Carmen M Valenzuela-Silva, Omar Ramírez-Nuñez, Mayté Casanova-Orta, María A Robinson-Agramonte, Ileana Lopategui-Cabezas and Pedro A López-Saura
    Citation: Journal of Inflammation 2009 6:18
    Content type: Research Published on:

  14. Recently, it has been reported that the Gly573Ser substitution of transient receptor potential V3 (TRPV3) leads to increased ion-channel activity in keratinocytes. Our previous studies have indicated that the ...

    Authors: Kinichi Imura, Takeshi Yoshioka, Tsutomu Hirasawa and Tsuneaki Sakata
    Citation: Journal of Inflammation 2009 6:17
    Content type: Research Published on:

  16. Cystic Fibrosis (CF) is one of the most common autosomal genetic disorders in humans. This disease is caused by mutations within a single gene, coding for the cystic fibrosis transmembrane conductance regulato...

    Authors: Rangan Maitra, Melissa A Porter, Shan Huang and Brian P Gilmour
    Citation: Journal of Inflammation 2009 6:15
    Content type: Short Report Published on:

  18. Zymosan-induced shock has been associated with an increased production of pro-inflammatory cytokines and mediators, causing a generalized dysfunction of liver, lung and kidneys. Herein, we investigate the effe...

    Authors: Petya Dimitrova, Valeriya Gyurkovska, Irina Shalova, Luciano Saso and Nina Ivanovska
    Citation: Journal of Inflammation 2009 6:13
    Content type: Research Published on:

  19. Toll-like receptors (TLRs) are present on monocytes and alveolar macrophages that form the first line of defense against inhaled particles. The importance of those cells in the pathophysiology of chronic obstr...

    Authors: Hadi Sarir, Esmaeil Mortaz, Khalil Karimi, Aletta D Kraneveld, Irfan Rahman, Eric Caldenhoven, Frans P Nijkamp and Gert Folkerts
    Citation: Journal of Inflammation 2009 6:12
    Content type: Research Published on:

  20. The mast cell is a crucial effector cell in allergic rhinitis and other inflammatory diseases. During the acute allergic reaction preformed mediators such as histamine, but also de novo produced mediators such as...

    Authors: Joke Patou, Gabriele Holtappels, Karen Affleck, Philippe Gevaert, Claudina Perez-Novo, Paul Van Cauwenberge and Claus Bachert
    Citation: Journal of Inflammation 2009 6:11
    Content type: Research Published on:

  21. Interleukin-6 is a multifunctional cytokine that is critical for T/B-cell differentiation and maturation, immunoglobulin secretion, acute-phase protein production, and macrophage/monocyte functions. Extensive ...

    Authors: Bailin Liang, Zheng Song, Bin Wu, Debra Gardner, David Shealy, Xiao-Yu Song and Paul H Wooley
    Citation: Journal of Inflammation 2009 6:10
    Content type: Research Published on:

  23. Inflammation is a major component of obesity and diabetes, and toll-like receptors (TLRs) play critical roles in the regulation of inflammation and response to pathogen associated molecular patterns (PAMPs) an...

    Authors: Kolapo M Ajuwon, William Banz and Todd A Winters
    Citation: Journal of Inflammation 2009 6:8
    Content type: Research Published on:

  25. Obesity is a leading risk factor for metabolic syndrome whose further expression is non-alcoholic fatty liver disease. Metabolic syndrome is associated with a proinflammatory state that contributes to insulin ...

    Authors: Giovanni Tarantino, Patrizia Colicchio, Paolo Conca, Carmine Finelli, Matteo Nicola Dario Di Minno, Marianna Tarantino, Domenico Capone and Fabrizio Pasanisi
    Citation: Journal of Inflammation 2009 6:6
    Content type: Research Published on:

  26. We are reporting for the first time the in vivo anti-inflammatory activity of extracts and fractions, and in vitro anti-inflammatory activity of pure compounds, all isolated from Pseudopterogorgia elisabethae col...

    Authors: Hebelin Correa, Alba Lucia Valenzuela, Luis Fernando Ospina and Carmenza Duque
    Citation: Journal of Inflammation 2009 6:5
    Content type: Research Published on:

  28. Prolylcarboxypeptidase (Prcp) gene, along with altered PRCP and kallikrein levels, have been implicated in inflammation pathogenesis. PRCP regulates angiotensin 1–7 (Ang 1–7) – and bradykinin (BK) – stimulated ni...

    Authors: My-Linh Ngo, Fakhri Mahdi, Dhaval Kolte and Zia Shariat-Madar
    Citation: Journal of Inflammation 2009 6:3
    Content type: Research Published on:

  29. Extracts of the creosote bush, Larrea tridentata, have been used for centuries by natives of western American and Mexican deserts to treat a variety of infectious diseases and inflammatory disorders. The benefici...

    Authors: D Eads, RL Hansen, AO Oyegunwa, CE Cecil, CA Culver, F Scholle, ITD Petty and SM Laster
    Citation: Journal of Inflammation 2009 6:2
    Content type: Research Published on:

  30. Mast cells and basophils are multifunctional effector cells and contain plentiful secretary granules in their cytoplasm. These cell types are involved in several inflammatory and immune events and are known to...

    Authors: Zafar Rasheed, Nahid Akhtar, Arivarasu N Anbazhagan, Sangeetha Ramamurthy, Meenakshi Shukla and Tariq M Haqqi
    Citation: Journal of Inflammation 2009 6:1
    Content type: Research Published on:

  31. The mechanisms responsible for the development of allergic rhinitis(AR) are not fully understood. The present study was designed to explore the possible roles of carbon monoxide(CO) on the pathogenesis of AR.

    Authors: Yu Shaoqing, Zhang Ruxin, Chen Yinjian, Chen Jianqiu, Zhu Chunsheng, Tang Jiangfeng and Li Genhong
    Citation: Journal of Inflammation 2008 5:23
    Content type: Research Published on:

  32. Evaluate the potential role of p38 inhibitors for the treatment of osteoarthritis using an animal model of joint degeneration (iodoacetate-induced arthritis) and a pain model (Hargraeves assay).

    Authors: Kimberly K Brown, Sandra A Heitmeyer, Erin B Hookfin, Lily Hsieh, Maria Buchalova, Yetunde O Taiwo and Michael J Janusz
    Citation: Journal of Inflammation 2008 5:22
    Content type: Research Published on:

  33. Cigarette smoke-induced cellular and molecular mechanisms of lung injury are not clear. Cigarette smoke is a complex mixture containing long-lived radicals, including p-benzosemiquinone that causes oxidative d...

    Authors: Shuvojit Banerjee, Ranajoy Chattopadhyay, Arunava Ghosh, Hemanta Koley, Koustubh Panda, Siddhartha Roy, Dhrubajyoti Chattopadhyay and Indu B Chatterjee
    Citation: Journal of Inflammation 2008 5:21
    Content type: Research Published on:

  34. The balance between reactive oxygen species (ROS) and endogenous anti-oxidants is important in maintaining healthy tissues. Excessive ROS states occur in diseases such as ARDS and Idiopathic Pulmonary Fibrosis...

    Authors: Michael Eberlein, Kara A Scheibner, Katharine E Black, Samuel L Collins, Yee Chan-Li, Jonathan D Powell and Maureen R Horton
    Citation: Journal of Inflammation 2008 5:20
    Content type: Research Published on:

  35. Coeliac disease (CD) is an enteropathy characterized by an aberrant immune response to cereal-gluten proteins. Although gluten peptides and microorganisms activate similar pro-inflammatory pathways, the role t...

    Authors: Marcela Medina, Giada De Palma, Carmen Ribes-Koninckx, Miguel Calabuig and Yolanda Sanz
    Citation: Journal of Inflammation 2008 5:19
    Content type: Research Published on:

  36. Proteinase-activated receptor 2 (PAR-2), activated by trypsin and other serine proteinases, is a key initiator of inflammatory responses in the intestine of mammals. Atlantic salmon fed diets with standard qua...

    Authors: Jim Thorsen, Einar Lilleeng, Elin Christine Valen and Ã…shild Krogdahl
    Citation: Journal of Inflammation 2008 5:18
    Content type: Research Published on:

  37. Lysophosphatidylcholines (lysoPCs) are products of phospholipase A2 (PLA2) enzyme activity, and like the enzyme, have a direct role in toxic inflammatory responses in variety of organ systems. Paradoxically, r...

    Authors: Timothy J Cunningham, Lihua Yao and Angel Lucena
    Citation: Journal of Inflammation 2008 5:17
    Content type: Research Published on:

  38. House dust mite (HDM) allergens are a major cause of allergic asthma. Most studies using animal models of allergic asthma have used rodents sensitized with the 'un-natural' allergen ovalbumin. It has only rece...

    Authors: Robert J Bischof, Ken J Snibson, Joanne Van Der Velden and Els NT Meeusen
    Citation: Journal of Inflammation 2008 5:16
    Content type: Research Published on:

  39. Previous studies in our lab have identified Pre-B-cell colony enhancing factor (PBEF) as a novel biomarker in acute lung injury (ALI). The molecular mechanism of PBEF involvement in the pathogenesis of ALI is ...

    Authors: Hailong Li, Peng Liu, Javier Cepeda, Deyu Fang, R Blaine Easley, Brett A Simon, Li Qin Zhang and Shui Qing Ye
    Citation: Journal of Inflammation 2008 5:15
    Content type: Research Published on:

  40. The Infiltration of leukocytes across the brain endothelium is a hallmark of various neuroinflammatory disorders. Under inflammatory conditions, there is increased expression of specific cell adhesion molecule...

    Authors: Ratna Prasad, Shailendra Giri, Avtar K Singh and Inderjit Singh
    Citation: Journal of Inflammation 2008 5:14
    Content type: Research Published on:

  41. Carbon monoxide (CO) has recently been suggested to have anti-inflammatory properties, but data seem to be contradictory and species-specific. Thus, in studies on macrophages and mice, pretreatment with CO att...

    Authors: Anna-Maja Åberg, Pernilla Abrahamsson, Göran Johansson, Michael Haney, Ola Winsö and Jan Erik Larsson
    Citation: Journal of Inflammation 2008 5:13
    Content type: Research Published on:

  42. The cytoprotective nature of nitric oxide (NO) led to development of NO-aspirins in the hope of overcoming the gastric side-effects of aspirin. However, the NO moiety gives these hybrids potential for actions ...

    Authors: Catriona M Turnbull, Paolo Marcarino, Tara A Sheldrake, Loretta Lazzarato, Clara Cena, Roberta Fruttero, Alberto Gasco, Sarah Fox, Ian L Megson and Adriano G Rossi
    Citation: Journal of Inflammation 2008 5:12
    Content type: Research Published on:

  44. Circulating 25 hydroxyvitamin D (25 (OH)D), an accurate measure of vitamin D status, is markedly greater in individuals with increased exposure to ultraviolet B (UVB) light via sunlight or the use of artificia...

    Authors: Catherine A Peterson and Mary E Heffernan
    Citation: Journal of Inflammation 2008 5:10
    Content type: Research Published on:

  45. Several recent studies have documented that supplementation with pomegranate fruit extract inhibits inflammatory symptoms in vivo. However, the molecular basis of the observed effects has not been fully revealed....

    Authors: Meenakshi Shukla, Kalpana Gupta, Zafar Rasheed, Khursheed A Khan and Tariq M Haqqi
    Citation: Journal of Inflammation 2008 5:9
    Content type: Research Published on:

  46. Intercellular adhesion molecule-1 (ICAM-1) is a critical target-docking molecule on epithelial cells for 90% of human rhinovirus (HRV) serotypes. Two forms of ICAM-1 exist, membranous (mICAM-1) and soluble (sI...

    Authors: Suzanne C Whiteman and Monica A Spiteri
    Citation: Journal of Inflammation 2008 5:8
    Content type: Research Published on:

  47. Bee venom therapy has been used to treat inflammatory diseases including rheumatoid arthritis in humans and in experimental animals. We previously found that bee venom and melittin (a major component of bee ve...

    Authors: Hye Ji Park, Hwa Jeong Lee, Myung Sook Choi, Dong Ju Son, Ho Sueb Song, Min Jong Song, Jeong Min Lee, Sang Bae Han, Youngsoo Kim and Jin Tae Hong
    Citation: Journal of Inflammation 2008 5:7
    Content type: Research Published on:

  48. The tripeptide feG (D-Phe-D-Glu-Gly) is a potent anti-inflammatory peptide that reduces the severity of type I immediate hypersensitivity reactions, and inhibits neutrophil chemotaxis and adhesion to tissues. ...

    Authors: Ronald D Mathison, Emily Christie and Joseph S Davison
    Citation: Journal of Inflammation 2008 5:6
    Content type: Research Published on:

  49. The epidermal growth factor (EGF) and EGF receptor (EGFR) families play important roles in the hyperplastic growth of several tissues as well as tumor growth. Since synovial hyperplasia in rheumatoid arthritis...

    Authors: Shoji Yamane, Satoru Ishida, Yukie Hanamoto, Ken-ichi Kumagai, Riako Masuda, Konagi Tanaka, Noriyuki Shiobara, Noriko Yamane, Toshihito Mori, Takuo Juji, Naoshi Fukui, Tsunetoshi Itoh, Takahiro Ochi and Ryuji Suzuki
    Citation: Journal of Inflammation 2008 5:5
    Content type: Research Published on:

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