Fig. 3

AAT reduced the number of macrophages in the retina of phase II OIR mice at postnatal day 18. RA, room air. Con, control. HSA, human serum albumin. AAT, alpha-1 antitrypsin. A. Gating strategy for CD45^midCD11b⁺ microglia and CD45^hiCD11b⁺ macrophages. Fold change in the density (B) and total cell count (C) of CD45^midCD11b⁺ cells in retina. Fold change in the density (D) and total cell count (E) of CD45^hiCD11b⁺ cells in retina. n = 4 to 16 mice per group. Values are mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. Data were analysed by Welch’s ANOVA followed by Dunnett’s T3 test