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Table 1 Clinical and biochemical characteristics of the included clinical trials

From: Effect of statins on arterial wall inflammation as assessed by 18F-FDG PET CT: an updated systematic review and meta-analysis

Author

Study design

Target Population

Treatment duration

n

Study groups

Boczar et al. 2022 [33]

Prospective randomized trial

HIV infection

6 months

17

18

Rosuvastatin 10 mg/day

Control

Emami et al. 2015 [34]

Open-label trial

History of atherosclerosis

3 months

24

24

Atorvastatin 80 mg/day

Placebo

Ishii et al. 2010 [42]

Randomized, open-label trial

Adults with stable angina pectoris

6 months

15

15

Atorvastatin 5 mg/day

Atorvastatin 20 mg/day

Kim et al. 2020 [35]

Prospective interventional

study

Acute coronary syndrome

1 month

13

Atorvastatin 20 mg/day

Lo et al. 2015 [36]

Randomized, double-blind, placebo-controlled

HIV-infected patients

1 year

17

20

Atorvastatin 40 mg/day

Placebo

Subramanian et al. 2013 [37]

Randomized, double-blind, active-controlled

Adults with risk factors or with established atherosclerosis

3 months

29

29

Atorvastatin 10 mg/day

Atorvastatin 80 mg/day

Tawakol et al. 2013 [38]

Randomized, double-blind trial

Individuals with arterial inflammation

3 months

34

34

Atorvastatin 10 mg/day

Atorvastatin 80 mg/day

van der Valk et al. 2016 [41]

Open-label trial

Patients with ankylosing spondylitis

3 months

18

Atorvastatin 40 mg/day

Watanabe et al. 2015 [39]

Randomized, open-label trial

Patients with hyperlipidemia

6 months

10

10

Pitavastatin 2 mg/day

Pravastatin 10 mg/day

Wu et al. 2012 [40]

Open-label trial

Patients with atherosclerosis

3 months

43

34

Atorvastatin 40 mg/day

Control