Fig. 2
From: Non-ionic surfactant vesicles exert anti-inflammatory effects through inhibition of NFκB
NISV alter the metabolism of BMDM following LPS stimulation. 100,000 BMDM were plated per well as 10 replicates and stimulated with LPS at 3 µg/ml or media, in controls, followed by treatment with NISV. Samples were pooled to make 1,000,000 cells/sample. Cells then underwent metabolite extraction and were sent for metabolomics analysis. Pathway diagrams indicated metabolite detection in green and non-detection in black. A shows NISV effects on glycolysis, B shows their effects on the TCA cycle. Statistical analysis was performed on prism 8 using two-way ANOVA and Tukey’s multiple comparisons test. * Indicates statistical significance (p < 0.05)