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Fig. 7 | Journal of Inflammation

Fig. 7

From: Transcriptional pathways of terminal differentiation in high- and low-density blood granulocytes in sepsis

Fig. 7

Quantitation of CD63, PLAC8, and CEACAM4 expression in the granulocyte fractions and C-reactive protein (CRP) in plasma. Patient subgroup medians are represented by horizontal lines. Superscripts to the gene names identify granulocyte preparations. Total granulocytes from 14 patients with sepsis and 16 with SIRS were analyzed by qRT-PCR. Accordingly, high-density (HD) and low-density (LD) granulocytes from 11 patients with sepsis and 14 with SIRS were analyzed. Panel (A) summarizes the cycle threshold (Ct) values for all measurements. Total granulocyte levels of CD63 and PLAC8 were referenced to CEACAM4 from the total granulocytes (B) and LD granulocyte levels to CEACAM4 from the HD fraction (C). Routine lab values for CRP are shown for the same patients contributing total granulocytes to the QRT-PCR analysis (D). The p-values from the Mann-Whitney U test are indicated

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Journal of Inflammation

ISSN: 1476-9255

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