Fig. 5

Cytokine levels detected in the blood and brain of saline and LPS-administered animals. Blood cytokines were evaluated at 8h and 24h after injection while brain tissue was evaluated at 24 h after injections. The difference, in log fold change, in cytokine production of LPS-administered animals to control is shown in (A). The levels of CXCL1, TGFβ, IL-18, IL-23, CCL22, IL-10, IL-6, TNFα, G-CSF, CCL17, IL-12p40, and IL-1β are shown in (B) - (M) respectively. Each dot represents a single animal. Statistical differences are shown as ns: not significant, *p<0.05, **p<0.01, ***p<0.001