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Fig. 2 | Journal of Inflammation

Fig. 2

From: Mulberroside A mitigates intervertebral disc degeneration by inhibiting MAPK and modulating Ppar-γ/NF-κB pathways

Fig. 2

MA inhibited IL-1β-stimulated ECM degeneration in NPCs. (A-D) The expressions of anabolic-related proteins (Aggrecan, Collagen II, and Collagen I) and catabolic-related proteins (Mmp2, Mmp3, Mmp9, and Mmp13) in NPCs were analyzed with western blotting. (E-G) the expressions of Collagen II and Mmp13 were detected by immunofluorescence, scalebar = 200 μm. (H) The mRNA expression of Collagen II and Mmp13 were analyzed by RT-qPCR. Data were shown as means ± SD, n = 3. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ns, no significant difference

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Journal of Inflammation

ISSN: 1476-9255

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