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Fig. 2 | Journal of Inflammation

Fig. 2

From: Emodin alleviates intestinal ischemia–reperfusion injury through antioxidant stress, anti-inflammatory responses and anti-apoptosis effects via Akt-mediated HO-1 upregulation

Fig. 2

A Different doses of Emodin attenuated II/R-associated apoptosis. The Emodin doses of 40 mg/kg and 80 mg/kg significantly attenuated II/R-associated apoptosis compared to the 20 mg/kg Emodin dose. B Different doses of Emodin inhibited apoptosis by down-regulating pro-apoptosis associated proteins such as cleaved Caspase-3/Caspase-3 and Bax, and up-regulating anti-apoptosis associated protein such as Bcl-2. Emo20: II/R plus 20 mg/kg Emodin, Emo40: II/R plus 40 mg/kg Emodin, Emo80: II/R plus 80 mg/kg Emodin. Quantitative analysis of the expression compared with β-actin was shown beside

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Journal of Inflammation

ISSN: 1476-9255

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