Fig. 5
From: Coarse particulate matter (PM10) induce an inflammatory response through the NLRP3 activation
Exposure to PM10 induces an inflammatory response in the lungs. The gene expression of inflammatory components was quantified by qPCR from lung tissue of C57BL6 mice exposed to PM10. Results are presented as RTU (relative transcript units) x 103 for (A) NLRP3, (B) Casp-1, (C) IL-1β, (D) IL-18, (E) IL-6, (F) CXCL1 and (G) MUC5AC and as pg/mL (H) IL-6 in BALF and (I) IL-6 in serum. Mice exposed to PBS were used as a negative control. The data were represented as median ± IQR (n = 6). Statistical comparison was made using the Kruskal-Wallis test with a confidence level of 95%, and Dunn’s HDS post hoc (or multiple reference points) tests were applied. Significant differences * p < 0.05; ** p < 0.01; ***p < 0.001