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Fig. 2 | Journal of Inflammation

Fig. 2

From: Crtc1 deficiency protects against sepsis-associated acute lung injury through activating akt signaling pathway

Fig. 2

Crtc1 knockout alleviated CLP-induced apoptosis in ALI.(A, B) Representative TUNEL staining images (A) and quantification data (B) showing the impact of Crtc1 KO on CLP-induced apoptosis in lung tissues. ***P < 0.001 vs. Crtc1+/+; ###P < 0.001 vs. Sham. n = 6. (C-F) Western blot (C) and quantification (D-F) showing the protein level of Cleaved-caspase3/Caspase3 (D), Bcl-2 (E) and Bax (F) in mice lung tissues. *P < 0.05, **P < 0.01 vs. Crtc1+/+; #P < 0.05, ##P < 0.01 vs. Sham; n = 3

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