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Fig. 6 | Journal of Inflammation

Fig. 6

From: The TFPI2–PPARγ axis induces M2 polarization and inhibits fibroblast activation to promote recovery from post-myocardial infarction in diabetic mice

Fig. 6

Effects of TFPI2 overexpression on macrophage polarization in diabetic MI mice

(a) Co-immunofluorescence staining of the macrophage marker (CD68, green) and M1 marker (CD86, red) in the infarcted myocardium samples (n = 3, respectively). (b) Co-immunofluorescence staining of the macrophage marker (CD68, green) and M2 marker (CD206, red) in the infarcted myocardium samples (n = 3). (c) Western blot analysis of iNOS, Arg-1, and PPARγ at 3 weeks after infarction (n = 3). MI, myocardial infarction; DM, diabetes mellitus; TFPI2, transfection with TFPI2 cDNA; vector, transfection with the empty vector. Data represent mean ± standard deviation (SD). Data were analyzed using one-way ANOVA and Tukey’s post hoc test. *P < 0.05, **P < 0.01, ***P < 0.001

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Journal of Inflammation

ISSN: 1476-9255

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