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Table 4 List of CXCL8-CXCR2 inhibitors in clinical trials

From: The immunological function of CXCR2 in the liver during sepsis

Target

Drugs

Current status

Clinical Trials Identifier

CXCL8

Antibodies

HuMax-IL8

Malignant solid tumor [157]

NCT02536469

CXCR2

Small molecular inhibitors

Reparixin

IRI of liver transplant [158]; tumor [159]

NCT03031470;

NCT02370238;

Danirixin

COPD [160]; viral disease [161]

NCT03034967;

NCT02469298