Fig. 3

The systemic inflammatory response and organ damage was decreased by reducing LPS-load in the liver. a-b liver occlusion inhibited the LPS induced hepatic TNF-a (a), and IL-6 (b) mRNA expression. c-d The expression of CCL-2 and CCL-3 mRNA levels in liver tissues. LPS induced upregulation of hepatic CCL-2 (c) and CCL-3 (d) mRNA expression was inhibited by liver occlusion. e The hepatic influx of neutrophil was analyzed by counting ASDCL positive cells. The neutrophil infiltration to occluded liver lobes was significantly lower compared to non-occluded lobes. *P<0.05, **P<0.01