Fig. 6

Effect of tofacitinib on intrarectally infused IFNγ-induced pSTAT1 production in mouse colon. Data (mean ± SEM, n = 4–11) are expressed with respect to (a) dose and (b) concentration. (c) Concentration/response curve to tofacitinib in the mouse isolated colon with respect to IFNγ-induced pSTAT1 production (mean ± SEM, n = 3–18)