Figure 2

Relative levels of transcripts encoding enzymes in the kynurenine pathway (A-J) following treatment with IFN-γ (200 U/ml), TNF-α (100 U/ml) or the combination of these two cytokines (IFN-γ+TNF-α) during 48 hrs in serum-free cell culture medium (n = 7). Levels of all transcripts are normalized to levels observed in untreated control cells (base-line). *p < 0.05, **p < 0.01, ***p < 0.001.