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Table 4 Clinical characteristics of CKD patients with different AT1Rgenotypes

From: Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease

 

AA

(n = 28)

AC+CC

(n = 48)

P- value

Age(Years)

10.13 ± 4.15

10.97 ± 3.36

0.45

SBP(mmHg)

128 ± 17.81

120.5 ± 15.56

0.85

DBP(mmHg)

83.33 ± 12.91

81.10 ± 11.56

0.52

Total cholesterol(mg/dl)

202.44 ± 55.25

177.50 ± 49.51

0.85

Triglycerides(mg/dl)

133.43 ± 71.98

153.08 ± 59.95

0.47

HDL-Cholesterol (mg/dl)

26.18 ± 11.54

30.25 ± 18.09

0.36

Creatinine(mg/dl)

5.64 ± 1.63

6.72 ± 1.29

0.23

Urea(mg/dl)

60.00 ± 12.85

80.65 ± 21.36

0.04*

hs-CRP, mg/dl

4.28 ± 4.06

2.70 ± 2.91

0.43

CK-MB(ng/ml)

5.14 ± 1.10

5.58 ± 1.29

0.52

Hypertensive%

57.14%

47.92%

0.65

ACE activity(IU/l)

61.85 ± 54.91

84.26 ± 55.89

0.04*

Left ventricular mass index(g/m 2.7 )

53.88 ± 9.33

52.33 ± 11.02

0.52

Severe left ventricular hypertrophy, n (%)

11(39.29%)

20(41.76%)

0.62

  1. Significance was estimated using independent t-test. Data was means ± SD. SBP = systolic blood pressure, DBP = diastolic blood pressure, hs-CRP = high sensitivity C- reactive protein, CK-MB = creatine kinase-MB fraction. *P < 0.05 was considered significant.
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Journal of Inflammation

ISSN: 1476-9255

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