Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

Skip to main content

Table 1 Effect of colitic inducers, TNBS and DSS, on lipid peroxide (malondialdehyde, MDA), 4-hydroxy-2-nonenal (4-HNE), and glutathione (GSH) contents and superoxide dismutase (SOD), and catalase activities in the colons of C3H/HeN and C3H/HeJ mice

From: Dextran sulfate sodium and 2,4,6-trinitrobenzene sulfonic acid induce lipid peroxidation by the proliferation of intestinal gram-negative bacteria in mice

 

Colitic inducer

Content

Activity

  

MDA (μM/mg)

4-HNE(ng/ml)

GSH(μg/ml)

SOD(Unit/mg)

Catalase(mol/min/mg)

C3H/HeN

-a

0.74 ± 0.51

0.86 ± 0.85

1.51 ± 1.14

3.76 ± 1.30

5.22 ± 1.33

 

DSS

5.60 ± 1.04#

11.92 ± 7.01#

4.53 ± 0.15#

1.06 ± 0.13#

0.19 ± 0.94#

C3H/HeJ

-a

0.72 ± 0.56

2.52 ± 3.11

0.67 ± 0.38

5.21 ± 1.83

6.25 ± 1.21

 

DSS

5.39 ± 1.00#

2.93 ± 2.26#

4.57 ± 0.12#

0.72 ± 0.17#

0.60 ± 1.41#

C3H/HeN

-a

0.99 ± 0.09

3.31 ± 0.15

4.92 ± 1.33

3.39 ± 0.34

7.53 ± 0.77

 

TNBS

5.11 ± 0.67#

15.92 ± 4.03#

2.19 ± 0.24#

0.16 ± 0.04#

1.49 ± 1.00#

C3H/HeJ

-a

0.66 ± 0.06

1.53 ± 1.80

4.38 ± 0.93

3.64 ± 0.47

4.76 ± 0.65

 

TNBS

2.95 ± 0.94#

3.57 ± 0.89#

2.13 ± 0.25#

0.50 ± 0.03#

0.82 ± 0.65#

  1. The test agents were orally administered once every day for 3 days prior to TNBS treatment. The mice were anesthetized with ether and killed 3 days after TNBS treatment.
  2. a) Normal group treated with vehicle alone instead of colitic inducer.
  3. All values are the mean ± S.D. (n = 10). #Significantly different vs normal group in each column of C3H/HeN or C3H/HeJ mice (P < 0.05).