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Table 2 Fat cells are not required for the up-regulation of IL-8 release and IL-8 mRNA seen in nonfat cells over a 48 h incubation

From: The inflammatory response seen when human omental adipose tissue explants are incubated in primary culture is not dependent upon albumin and is primarily in the nonfat cells

IL-8 mRNA

Change in tissue after 48 h [ratio]

% Change in nonfat cells incubated for 48 h as compared to tissue

% Change in nonfat cells isolated after 48 h as compared to tissue

 

832-X

+38 ± 17%

+3 ± 12%

IL-8 release

48 h release by tissue in pmoles/g

% Change in nonfat cells incubated for 48 h as compared to tissue

 
 

1450

+1 ± 16%

 
  1. The change in IL-8 mRNA at 48 h is the fold-change derived from the ΔCp over 48 h of -9.6 ± 0.3. The values are from 8 experiments and the % changes are the mean ± SEM of the paired differences. None were statistically significant with a P < 0.05.
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Journal of Inflammation

ISSN: 1476-9255

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