Figure 6
From: Modulation of expression and cellular distribution of p21 by macrophage migration inhibitory factor
rMIF treatment of MIF-/- MDF induces p21 expression and nuclear localisation. No difference in p21 immunofluorescence was observed when MIF replete wt MDF were treated with rMIF. In contrast, compared with vehicle (V), rMIF treated MIF-/- MDF exhibited increased expression and nuclear localisation of p21 (N = 4).