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Editors' Pick: SARS-CoV-2 COVID-19 Susceptibility and Lung Inflammatory Storms by Smoking and Vaping
Aging, smoking/vaping results in severe disease outcome and mortality amongst COVID-19 patients. SARS-CoV-2 with a membrane spike glycoprotein furin along with its receptor ACE2 and TMPRSS2 protease are increased by smoking/vaping in lung epithelium rendering viral entry and augmented infection. This results in a ‘cytokine storm’ involving excessive production of pro-inflammatory cytokines/chemokines. This review therefore discusses the impact of smoking /vaping on the key inflammatory mechanisms following Covid-19 infection and the possible therapeutic strategies required to overcome this excessive inflammatory response.
From theory to therapy; understanding and targeting immunometabolism for the treatment of inflammation and cancer
Edited by:
Dr. Peter Bunyard, Ph.D., Sitryx Therapeutics, United Kingdom
Dr. pharm. Marina Makrecka-Kuka, Ph.D., Sitryx Therapeutics, United Kingdom
Submission Status: Open until 15 July 2025
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Biological mechanisms and therapeutic prospects of interleukin-33 in pathogenesis and treatment of allergic disease
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Comparison of the inflammatory biomarkers IL- 6, TNF-α, and CRP to predict the effect of nutritional therapy on mortality in medical patients at risk of malnutrition
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Mucosal immunotherapy targeting APC in lung disease
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Exploring the mitigating potential of anthocyanin Malvidin in a mouse model of bleomycin-induced pulmonary fibrosis by inhibiting NLRP3 inflammasome activation and oxidative stress
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Anti-inflammatory potential of Quercetin in COVID-19 treatment
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Increased serum complement C3 and C4 concentrations and their relation to severity of chronic spontaneous urticaria and CRP concentration
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The Journal of Inflammation
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Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells
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Mesenchymal stem cells avoid allogeneic rejection
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Testing the boundaries of the brain’s immune system
Edited by:
Laura McCulloch: University of Edinburgh, UK
Andrew Greenhalgh: University of Manchester, UK
Submission Status: Open until 1 December 2024
Aims and scope
Journal of Inflammation is an open access, peer-reviewed online journal publishing articles on all aspects of research into inflammation. Non-research articles are specially commissioned by the Editors-in-Chief.
Announcing the launch of In Review
Journal of Inflammation, in partnership with Research Square, is now offering In Review. Authors choosing this free optional service will be able to:
- Share their work with fellow researchers to read, comment on, and cite even before publication
- Showcase their work to funders and others with a citable DOI while it is still under review
- Track their manuscript - including seeing when reviewers are invited, and when reports are received
Submit your review
Journal of Inflammation welcomes review articles on a variety of different topics relating to the scope of the journal. Submit your review today.
For further queries or to discuss the limited funds which may be available to cover the article-processing charge, please contact the editorial team.
Editor-in-Chiefs' profiles
Prof. Paul Kirkham, PhD, FHEA, FRSB, Professor of Cell Biology, University of Wolverhampton, United Kingdom
Professor Kirkham is Professor of Cell Biology at the University of Wolverhampton and a fellow of the HEA. His research interests focus on understanding the mechanisms of disease pathogenesis driven by oxidative stress and its impact on cell function and inflammation, particularly in relation to respiratory disease.
Prof. Adriano Rossi, PhD, DSc, FBS, FBPhS, University of Edinburgh, United Kingdom
Professor Rossi holds the position of Personal Chair in Respiratory and Inflammation Pharmacology at the University of Edinburgh. He is a Fellow of the Society of Biology and a Fellow of the British Pharmacological Society. His research involves investigating the cellular processes and signalling mechanisms controlling inflammation with a focus on understanding inflammation resolution.
Affiliated with the British Inflammation Research Association (BIRAs).
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Annual Journal Metrics
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Citation Impact 2023
Journal Impact Factor: 4.4
5-year Journal Impact Factor: 4.6
Source Normalized Impact per Paper (SNIP): 0.770
SCImago Journal Rank (SJR): 0.932Speed 2024
Submission to first editorial decision (median days): 18
Submission to acceptance (median days): 199Usage 2024
Downloads: 416,662
Altmetric mentions: 166